Best Practices in Cancer Nanotechnology: Perspective from NCI Nanotechnology Alliance

Best practices in cancer nanotechnology: perspective from NCI nanotechnology alliance.

Historically, treatment of patients with cancer using chemotherapeutic agents has been associated with debilitating and systemic toxicities, poor bioavailability, and unfavorable pharmacokinetics. Nanotechnology-based drug delivery systems, on the other hand, can specifically target cancer cells while avoiding their healthy neighbors, avoid rapid clearance from the body, and be administered wit...

NCI Alliance for Nanotechnology in Cancer Phase II Program Summary 2010-2015

Nanotechnology application in cancer treatment

Chemotherapy has been the main known treatment for cancer diseases. However, its achievement rate remains low, mainly because of the restricted accessibility of drugs to the tumor tissue, their painful toxicity, and development of multi-drug resistance. In recent years, either better understanding of tumor biology or development of the ever-growing field of nanotechnology has proposed new treat...

Application of Nanotechnology in Cancer Research: Review of Progress in the National Cancer Institute's Alliance for Nanotechnology

Cancer has become the leading cause of death among Americans today. In 2006, over 500,000 Ameri-cans will die due to cancer [11]. Cancer is a highly complex disease to understand because it entails multiple cellular physiological systems such as cell signal-ing and apoptosis [10]. Thus, the most common cancer treatments are limited to chemotherapy, radiation, and surgery. Limitations in cancer ...

Nanotechnology-Dermatological Perspective

Nanotechnology is the application of the science dealing with the study of small particles with dimensions of less than a hundred nanometers. Nanoparticles, owing to their size, have special physicochemical properties that are distinct from the derived bulk material. These nanoparticles have recently been employed for various diagnostic and therapeutic purposes and are particularly suited for u...